Trial intelligence / Profile preview

KRAS Peptide Vaccine + Nivolumab + Ipilimumab in Resected MMR-p Colorectal and Pancreatic Cancer

NCT04117087Phase 1Active, not recruiting

Sponsor
Sidney Kimmel Comprehensive Cancer Center
Start
May 2020
Primary completion
Jun 2027
Modality
Peptides, Vaccines & Immunotherapeutics
Countries
1
01

Overview

Phase 1, open-label trial of TG01 in colorectal cancer (CRC) and pancreatic cancer (PC) (2 arms), sponsored by Sidney Kimmel Comprehensive Cancer Center. Primary endpoints: Number of participants experiencing study drug-related toxicities at 2 years and Fold change in interferon-producing mutant-KRAS-specific cytotoxic (CD8) and helper (CD4) T cells at 16 weeks. Started May 2020; status: active, not recruiting.

02

Drugs

TG01
03

Conditions

colorectal cancer (CRC)pancreatic cancer (PC)

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