Trial intelligence / Profile preview

AMG 199 in MUC17-positive solid tumors

NCT04117958Phase 1Terminated

Sponsor
Amgen
Start
Jan 2020
Primary completion
Jun 2023
Modality
Antibody Conjugates, Bispecific Antibodies, Monoclonal Antibodies
Countries
9
01

Overview

Phase 1, open-label trial of amg 199 in gastric adenocarcinoma, gastroesophageal junction adenocarcinoma, colorectal cancer (CRC) and 1 more (2 arms), sponsored by Amgen. Primary endpoints: Dose-limiting toxicities at 3 years, Treatment-emergent adverse events at 3 years and 4 more. Started Jan 2020; status: terminated.

02

Drugs

amg 199
03

Conditions

gastric adenocarcinomagastroesophageal junction adenocarcinomacolorectal cancer (CRC)pancreatic ductal adenocarcinoma (PDAC)

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