Trial intelligence / Profile preview

Safety, PK, and Efficacy of ONC-392 as a Single Agent and in Combination With Pembrolizumab in Advanced Solid Tumors and NSCLC

NCT04140526Phase 2Active, not recruiting

Sponsor
OncoC4
Start
Sep 2020
Primary completion
Dec 2026
Modality
Engineered Antibody Formats, Antibody Conjugates, Monoclonal Antibodies
Countries
2
01

Overview

Phase 2, open-label trial of gotistobart in non-small cell lung cancer (NSCLC), solid tumor, melanoma and 16 more (3 arms), sponsored by OncoC4. Primary endpoints: Dose Limiting Toxicity at 21 days, Maximal Tolerable Dose at 21 days and 2 more. Started Sep 2020; status: active, not recruiting.

02

Drugs

gotistobart
03

Conditions

non-small cell lung cancer (NSCLC)solid tumormelanomahead and neck squamous cell carcinoma (HNSCC)renal cell carcinoma (RCC)

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