Trial intelligence / Profile preview

CARAPACE: NAC for Radiation Protection in Catheter Ablation

NCT04154982Phase 2Completed

Sponsor
Centro Cardiologico Monzino
Start
Sep 2020
Primary completion
Dec 2024
Modality
Small Molecules
Countries
1
01

Overview

Phase 2, randomised, single-blind trial of acetylcysteine in radiation-induced cellular damage, sponsored by Centro Cardiologico Monzino. Primary endpoint: Change in systemic oxidative stress (GSSG/GSH, 8-iso-PGF2α, 8-OHdG) and genomic DNA oxidative damage at 48 hours. Started Sep 2020; status: completed.

02

Drugs

acetylcysteine
03

Conditions

radiation-induced cellular damage

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