Trial intelligence / Profile preview

SLN124 in NTD Beta-thalassemia and Low Risk MDS

NCT04176653Phase 1Withdrawn

Sponsor
Silence Therapeutics
Start
Aug 2019
Primary completion
Sep 2021
Modality
Conjugated siRNA, Chemically Modified siRNA
Countries
2
01

Overview

Phase 1, randomised, double-blind trial of SLN124 in beta thalassemia and myelodysplastic syndrome (MDS) (5 arms), sponsored by Silence Therapeutics. Primary endpoints: Number of participants with all adverse events up to 2 months, 12 lead electrocardiogram parameters up to 2 months and 2 more. Planned start Aug 2019; status: withdrawn.

02

Drugs

SLN124
03

Conditions

beta thalassemiamyelodysplastic syndrome (MDS)

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