Trial intelligence / Profile preview

RIC Haplo-HCT for Hematologic Malignancies

NCT04191187Phase 2Completed

Sponsor
Moffitt Cancer Center
Start
Dec 2019
Primary completion
Feb 2024
Modality
Orthosteric Ligands, Metabolically Activated Prodrugs
Countries
1
01

Overview

Phase 2, open-label trial of fludarabine and melphalan in acute myeloid leukemia (AML), acute lymphoblastic leukemia (ALL), myelodysplastic syndrome (MDS) and 4 more, sponsored by Moffitt Cancer Center. Primary endpoint: Disease-Free Survival at 18 months. Started Dec 2019; status: completed.

02

Drugs

fludarabinemelphalan
03

Conditions

acute myeloid leukemia (AML)acute lymphoblastic leukemia (ALL)myelodysplastic syndrome (MDS)chronic myelogenous leukemia (CML)Myeloproliferative Neoplasm (MPN)

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