Trial intelligence / Profile preview

BLAST MRD AML-1: Pembrolizumab + Chemotherapy in AML

NCT04214249Phase 2Active, not recruiting

Sponsor
National Cancer Institute
Start
Feb 2021
Primary completion
Nov 2024
Modality
Immune Checkpoint Inhibitors, Recombinant Proteins and Enzymes
Countries
1
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Overview

Phase 2, randomised, open-label trial of pembrolizumab in acute myeloid leukemia (AML) (2 arms), sponsored by National Cancer Institute. Primary endpoints: Rate of Minimal Residual Disease (MRD) Negative - Complete Response (CR)/Complete Remission With Incomplete Recovery (CRi) at 78 days and Rate of MRD-negative CR at 33 days. Started Feb 2021; status: active, not recruiting.

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Drugs

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Conditions

acute myeloid leukemia (AML)

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