Trial intelligence / Profile preview

DOTS-AD: Optimal Treatment Sequences in Anxious Depression

NCT04245748Phase 4Recruiting

Sponsor
University of Cincinnati
Start
Mar 2020
Primary completion
Jul 2025
Modality
Small Molecules
Countries
1
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Overview

Phase 4, randomised, double-blind trial of escitalopram, duloxetine, clonazepam and pregabalin in mixed anxiety and depressive disorder (MADD), generalized anxiety disorder (GAD), Social Anxiety Disorder (SAD) and 2 more (2 arms), sponsored by University of Cincinnati. Primary endpoints: Hamilton Anxiety Rating at 20 weeks and Clinical Global Impression of Severity at 20 weeks. Started Mar 2020; status: recruiting.

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Drugs

escitalopramduloxetineclonazepampregabalin
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Conditions

mixed anxiety and depressive disorder (MADD)generalized anxiety disorder (GAD)Social Anxiety Disorder (SAD)separation anxiety disorder (SAD)panic disorder

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