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Hyperpolarized 13C Pyruvate Metabolic MRI to Predict Renal Tumor Aggressiveness

NCT04258462Phase 2Active, not recruiting

Start
Jan 2019
Primary completion
Oct 2026
Modality
Small Molecules
Countries
1
01

Overview

Phase 2, open-label trial of [1-13C]pyruvate in kidney neoplasm (2 arms). Primary endpoints: HP 13C pyruvate-to-lactate conversion measured by peak lactate/pyruvate ratio at 12 months, HP 13C pyruvate-to-lactate conversion measured by lactate/pyruvate area under curve (AUC) at 12 months and 1 more. Started Jan 2019; status: active, not recruiting.

02

Drugs

[1-13C]pyruvate
03

Conditions

kidney neoplasm

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