Trial intelligence / Profile preview

HQP1351 in refractory CML and Ph+ ALL

NCT04260022Phase 1Recruiting

Sponsor
Ascentage Pharma
Start
Jan 2020
Primary completion
Dec 2029
Modality
Small Molecules
Countries
2
01

Overview

Phase 1, randomised, open-label trial of olverembatinib in chronic myeloid leukemia (CML) and Philadelphia-chromosome positive acute lymphoblastic leukemia (4 cohorts), sponsored by Ascentage Pharma. Primary endpoints: Maximum Plasma Concentration of HQP1351 at 28 days and Area Under the Curve of HQP1351 at 28 days. Started Jan 2020; status: recruiting.

02

Drugs

olverembatinib
03

Conditions

chronic myeloid leukemia (CML)Philadelphia-chromosome positive acute lymphoblastic leukemia

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