Trial intelligence / Profile preview

Safety, Tolerability and PK of AZD2373 in Healthy Men of African Ancestry

NCT04269031Phase 1Completed

Sponsor
AstraZeneca
Start
Feb 2020
Primary completion
Aug 2021
Modality
Modified DNA Oligonucleotides, Single-strand DNA, Antisense Oligonucleotides (ASOs)
Countries
1
01

Overview

Phase 1, randomised, single-blind trial of opemalirsen in APOL1-mediated kidney disease (AMKD) (6 cohorts), sponsored by AstraZeneca. Primary endpoint: Number of subjects with adverse events and/or abnormal findings. Started Feb 2020; status: completed.

02

Drugs

opemalirsen
03

Conditions

APOL1-mediated kidney disease (AMKD)

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