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BK-CTLs for BK Virus Infection in Immunocompromised Transplant Patients
NCT04293042Phase 1Recruiting
- Sponsor
- Children's Hospital of Philadelphia
- Start
- Oct 2019
- Primary completion
- Jan 2028
- Modality
- Allogeneic CAR-T, Tumor-Infiltrating Lymphocytes (TILs), TCR-Engineered T Cells
- Countries
- 1
01
Overview
Phase 1, open-label, single-arm trial of BK-virus specific CTLs in BK polyomavirus infection, sponsored by Children's Hospital of Philadelphia. Primary endpoints: Number of participants with Grade III-IV acute GVHD at 8 weeks and Number of patients with undetectable BK viral load at 12 weeks. Started Oct 2019; status: recruiting.
02
Drugs
BK-virus specific CTLs
03
Conditions
BK polyomavirus infection
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