Trial intelligence / Profile preview

BrEAsT: BN-Brachyury, Entinostat, T-DM1, M7824 in Advanced Breast Cancer

NCT04296942Phase 1Terminated

Sponsor
National Cancer Institute
Start
May 2021
Primary completion
Oct 2021
Modality
Gene Editing, Immune Checkpoint Inhibitors, Small Molecules
Countries
1
01

Overview

Phase 1, open-label trial of bintrafusp alfa, MVA-BN-brachyury + FPV-brachyury and entinostat in breast cancer (3 cohorts), sponsored by National Cancer Institute. Primary endpoints: Overall Response Rate at 17 days and Incidence of Adverse Events at 17 days. Started May 2021; status: terminated.

02

Drugs

bintrafusp alfaMVA-BN-brachyury + FPV-brachyuryentinostat
03

Conditions

breast cancer

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