Trial intelligence / Profile preview

RECTIFHY: Colchicine for Vascular Function in Hypertension

NCT04303689Completed

Sponsor
University of Copenhagen
Start
Aug 2020
Primary completion
Dec 2022
Modality
Nucleic Acid-Directed Small Molecules, Classical Binding Small Molecules, Metabolically Activated Prodrugs
Countries
1
01

Overview

Randomised, double-blind trial in essential hypertension comparing Colchicine with Placebo (2 arms). Primary endpoints: Changes in vascular function with treatment measured as flowchanges with ultrasound doppler in response to infusions of isoprenaline at 3 weeks, Changes in vascular function with training measured as flowchanges with ultrasound doppler divided by changes in blood pressure measured with intraarterial canula, in response to infusions of… at 3 weeks and 1 more. Started Aug 2020; status: completed.

02

Drugs

colchicine
03

Conditions

essential hypertension

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