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Mechanisms of Hypertension in PCOS

NCT04327934Phase 1Terminated

Sponsor
Yale University
Start
Dec 2017
Primary completion
Jun 2022
Modality
Orthosteric Ligands, Peptides, Metabolically Activated Prodrugs
Countries
1
01

Overview

Phase 1, open-label trial of ganirelix and methyltestosterone in polycystic ovary syndrome (PCOS) and hypertension (HTN) (2 arms), sponsored by Yale University. Primary endpoints: Baroreflex Response to Lower Body Negative Pressure at Day 16, Free Plasma Testosterone Levels at Day 16 and 5 more. Started Dec 2017; status: terminated.

02

Drugs

ganirelixmethyltestosterone
03

Conditions

polycystic ovary syndrome (PCOS)hypertension (HTN)

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