Trial intelligence / Profile preview

Hyperpolarized Pyruvate (13C) MRI in Advanced Prostate Cancer

NCT04346225Phase 2Suspended

Start
Jul 2020
Primary completion
Dec 2026
Modality
Small Molecules
Countries
1
01

Overview

Phase 2, open-label trial of [1-13C]pyruvate in prostate cancer (PCa) (2 cohorts). Primary endpoints: Pyruvate to lactate (kPL) metabolic flux within target lesion at 1 day, Pyruvate to glutamate (kPG) metabolic flux within target lesion at 1 day and 2 more. Started Jul 2020; status: suspended.

02

Drugs

[1-13C]pyruvate
03

Conditions

prostate cancer (PCa)

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