Trial intelligence / Profile preview

PAveMenT: Palbociclib and Avelumab in Metastatic AR+ TNBC

NCT04360941Phase 1Active, not recruiting

Sponsor
Royal Marsden NHS Foundation Trust
Start
Aug 2020
Primary completion
Jul 2027
Modality
Immune Checkpoint Inhibitors, Recombinant Proteins and Enzymes, Small Molecules
Countries
1
01

Overview

Phase 1, open-label, single-arm trial of palbociclib and avelumab in breast cancer and triple-negative breast cancer (TNBC), sponsored by Royal Marsden NHS Foundation Trust. Primary endpoints: Maximum Tolerated Dose at 18 months and Objective Response Rate at 24 months. Started Aug 2020; status: active, not recruiting.

02

Drugs

palbociclibavelumab
03

Conditions

breast cancertriple-negative breast cancer (TNBC)

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