Trial intelligence / Profile preview

TBI with CLAG-M or FLAG-Ida before HCT for Relapsed/Refractory Myeloid Malignancies

NCT04375631Phase 1Recruiting

Sponsor
Fred Hutchinson Cancer Center
Start
Dec 2020
Primary completion
Feb 2027
Countries
1
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Overview

Phase 1, open-label trial in acute myeloid leukemia (AML), myelodysplastic syndrome (MDS), chronic myelomonocytic leukemia (CMML) and 3 more (2 arms), sponsored by Fred Hutchinson Cancer Center. Primary endpoints: Rate of hematopoietic cell transplantation failure at 200 days and Rate of disease progression at 200 days. Started Dec 2020; status: recruiting.

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Conditions

acute myeloid leukemia (AML)myelodysplastic syndrome (MDS)chronic myelomonocytic leukemia (CMML)mixed phenotype acute leukemia (MPAL)acute leukemia of ambiguous lineage (ALAL)

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