Trial intelligence / Profile preview

Ipilimumab and Nivolumab vs Temozolomide in Newly Diagnosed MGMT Unmethylated Glioblastoma

NCT04396860Phase 3Completed

Sponsor
National Cancer Institute
Start
Sep 2020
Primary completion
Jan 2023
Modality
Monoclonal Antibodies
Countries
1
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Overview

Phase 3, randomised, open-label trial of ipilimumab and nivolumab in glioblastoma (GBM) and Gliosarcoma (GS) (2 arms), sponsored by National Cancer Institute. Primary endpoints: Progression-free Survival up to 19.3 months and Overall Survival up to 19.3 months. Started Sep 2020; status: completed.

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Drugs

ipilimumabnivolumab
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Conditions

glioblastoma (GBM)Gliosarcoma (GS)

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