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18F-NOS PET/CT for Neuroinflammation in HIV and Opioid Use Disorder
NCT04401917Phase 1Completed
- Sponsor
- University of Pennsylvania
- Start
- Dec 2020
- Primary completion
- Jun 2025
- Modality
- Small Molecules
- Countries
- 1
01
Overview
Phase 1, open-label trial of 18F-NOS in opioid use disorder (OUD) and human immunodeficiency virus infection (HIV) (4 arms), sponsored by University of Pennsylvania. Primary endpoints: Patterns of [18F]NOS brain uptake in OUD+ vs. OUD- subjects at 3 years, Patterns of [18F]NOS brain uptake in HIV+ vs. HIV- subjects at 3 years and 1 more. Started Dec 2020; status: completed.
02
Drugs
18F-NOS
03
Conditions
opioid use disorder (OUD)human immunodeficiency virus infection (HIV)
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