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PK Study of Tolinapant with Itraconazole and Midazolam
NCT04411030Phase 1Completed
- Sponsor
- Astex Pharmaceuticals
- Start
- May 2020
- Primary completion
- Aug 2020
- Modality
- Small Molecules
- Countries
- 1
01
Overview
Phase 1, open-label trial of tolinapant in solid tumor and lymphoma (2 arms), sponsored by Astex Pharmaceuticals. Primary endpoints: Maximum Plasma Concentration (Cmax) of ASTX660, Area Under the Plasma Concentration-Time Curve from Time Zero to Last Quantifiable Concentration (AUC0-t) of ASTX660 and 6 more. Started May 2020; status: completed.
02
Drugs
tolinapant
03
Conditions
solid tumorlymphoma
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