Trial intelligence / Profile preview

4SCAR-T Therapy in CD19-Negative B-ALL

NCT04430530Phase 2Terminated

Sponsor
Shenzhen Geno-Immune Medical Institute
Start
Jun 2026
Primary completion
Jul 2026
Modality
Gene Editing, Gene Silencing, CAR-T Cells
Countries
1
01

Overview

Phase 2, open-label, single-arm trial of 4SCAR-T in B cell acute lymphoblastic leukemia (B-ALL), sponsored by Shenzhen Geno-Immune Medical Institute. Primary endpoint: Safety of fourth generation anti-CD22/CD123/CD38/CD10/CD20 CAR-T cells at 24 weeks. Started Jun 2026; status: terminated.

02

Drugs

4SCAR-T
03

Conditions

B cell acute lymphoblastic leukemia (B-ALL)

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