Trial intelligence / Profile preview

Tucatinib in HER2+ Gastrointestinal Cancers

NCT04430738Phase 2Active, not recruiting

Sponsor
Pfizer
Start
Sep 2020
Primary completion
Jul 2024
Modality
Small Molecules
Countries
2
01

Overview

Phase 2, open-label trial of tucatinib in colorectal carcinoma (CRC), gastric adenocarcinoma, gastroesophageal junction adenocarcinoma and 3 more, sponsored by Pfizer. Primary endpoints: Number of Participants With Renal Dose-Limiting Toxicities at 42 days and Number of Participants With Treatment Emergent Adverse Events at 20.7 months. Started Sep 2020; status: active, not recruiting.

02

Drugs

tucatinib
03

Conditions

colorectal carcinoma (CRC)gastric adenocarcinomagastroesophageal junction adenocarcinomaesophageal adenocarcinoma (EAC)cholangiocarcinoma (CCA)

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