Trial intelligence / Profile preview

ARCT-810 in stable OTCD

NCT04442347Phase 1Completed

Sponsor
Arcturus Therapeutics
Start
Nov 2020
Primary completion
Aug 2023
Modality
Gene Editing, Nanoparticles, Gene Silencing
Countries
1
01

Overview

Phase 1, randomised, double-blind trial in ornithine transcarbamylase deficiency comparing ARCT-810 with Placebo (2 arms). Primary endpoint: Incidence, severity and dose-relationship of adverse events at 4 weeks. Started Nov 2020; status: completed.

02

Drugs

ARCT-810
03

Conditions

ornithine transcarbamylase deficiency

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