Trial intelligence / Profile preview

Acalabrutinib PK study with Rabeprazole and Coca-Cola

NCT04489797Phase 1Completed

Sponsor
AstraZeneca
Start
Jul 2020
Primary completion
Aug 2020
Countries
1
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Overview

Phase 1, randomised, open-label trial of acalabrutinib tablet (Variant 1) in chronic lymphocytic leukemia (CLL), mantle cell lymphoma (MCL) and small lymphocytic lymphoma (SLL) (2 arms), sponsored by AstraZeneca. Primary endpoints: Area under plasma concentration-time curve from time zero to infinity, Area under the plasma concentration-time curve from time zero to time of last quantifiable concentration and 1 more. Started Jul 2020; status: completed.

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Drugs

acalabrutinib tablet (Variant 1)
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Conditions

chronic lymphocytic leukemia (CLL)mantle cell lymphoma (MCL)small lymphocytic lymphoma (SLL)

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