Trial intelligence / Profile preview

C-SMART: COVID-19 Prevention and Treatment in Cancer

NCT04534725Phase 3Completed

Sponsor
Peter MacCallum Cancer Centre
Start
Dec 2020
Primary completion
Nov 2022
Modality
Monoclonal Antibodies, Cytokines & Interferons, Small Molecules
Countries
1
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Overview

Phase 3, randomised, double-blind trial of interferon alfa, selinexor and lenzilumab in coronavirus disease 2019 (COVID-19) (4 arms), sponsored by Peter MacCallum Cancer Centre. Primary endpoints: Incidence of COVID-19 in cancer patients using interferon-alpha as prophylaxis without known positive contact with COVID-19 at 3 months, Incidence of any upper or lower community acquired respiratory viral infection at 3 months and 3 more. Started Dec 2020; status: completed.

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Drugs

interferon alfaselinexorlenzilumab
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Conditions

coronavirus disease 2019 (COVID-19)

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