Trial intelligence / Profile preview

Consolidative CD19 CAR T Cells After Allo-HSCT for B-cell Malignancies

NCT04556266Phase 1Withdrawn

Sponsor
Memorial Sloan Kettering Cancer Center
Start
Jul 2021
Primary completion
Mar 2022
Modality
Gene Editing, Gene Silencing, CAR-T Cells
Countries
1
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Overview

Phase 1, open-label trial of Vadacabtagene leraleucel in acute lymphoblastic leukemia (ALL), chronic lymphocytic leukemia (CLL) and B-cell non-Hodgkin lymphoma (4 cohorts), sponsored by Memorial Sloan Kettering Cancer Center. Primary endpoint: Maximum Tolerated Dose at 24 months. Planned start Jul 2021; status: withdrawn.

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Drugs

Vadacabtagene leraleucel
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Conditions

acute lymphoblastic leukemia (ALL)chronic lymphocytic leukemia (CLL)B-cell non-Hodgkin lymphoma

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