Trial intelligence / Profile preview

Safety and Tolerability of SLN124 in Healthy Volunteers

NCT04559971Phase 1Completed

Sponsor
Silence Therapeutics
Start
Sep 2020
Primary completion
Mar 2021
Modality
Conjugated siRNA, Chemically Modified siRNA
Countries
1
01

Overview

Phase 1, randomised, double-blind trial of SLN124 in beta thalassemia, myelodysplastic syndrome (MDS) and polycythemia vera (PV) (4 arms), sponsored by Silence Therapeutics. Primary endpoint: Incidence of treatment-emergent adverse events at 8 weeks. Started Sep 2020; status: completed.

02

Drugs

SLN124
03

Conditions

beta thalassemiamyelodysplastic syndrome (MDS)polycythemia vera (PV)

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