Trial intelligence / Profile preview

LCAR-M23 in relapsed and refractory epithelial ovarian cancer

NCT04562298Phase 1Terminated

Sponsor
Shanghai East Hospital
Start
Oct 2020
Primary completion
Jun 2022
Modality
CAR-T Cells
Countries
1
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Overview

Phase 1, open-label, single-arm trial of MSLN CAR-T TGFβRIIDN in epithelial ovarian cancer (EOC), sponsored by Shanghai East Hospital. Primary endpoints: Dose-limiting toxicity at 90 days, Treatment-emergent adverse events at 90 days and 2 more. Started Oct 2020; status: terminated.

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Drugs

MSLN CAR-T TGFβRIIDN
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Conditions

epithelial ovarian cancer (EOC)

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