Trial intelligence / Profile preview

Acalabrutinib NG Tube Bioavailability and PPI Interaction

NCT04564040Phase 1Completed

Sponsor
AstraZeneca
Start
Oct 2020
Primary completion
Dec 2020
Countries
1
01

Overview

Phase 1, randomised, open-label trial of acalabrutinib tablet (Variant 1) in mantle cell lymphoma (MCL) and coronavirus disease 2019 (COVID-19) (2 arms), sponsored by AstraZeneca. Primary endpoints: Area under plasma concentration-time curve from time zero to infinity at Day 2, Area under the plasma concentration time curve from time zero to time of last quantifiable concentration at Day 2 and 7 more. Started Oct 2020; status: completed.

02

Drugs

acalabrutinib tablet (Variant 1)
03

Conditions

mantle cell lymphoma (MCL)coronavirus disease 2019 (COVID-19)

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