Trial intelligence / Profile preview

Management of GI Events in TAK-788 Treated EGFR Exon 20 Insertion NSCLC

NCT04576208Phase 2Withdrawn

Sponsor
Takeda
Start
Nov 2020
Primary completion
Jul 2022
Modality
Fragment-Derived Small Molecules, Reversible Covalent Inhibitors, Bivalent/Multivalent Binders
01

Overview

Phase 2, randomised, open-label trial of mobocertinib in non-small cell lung cancer (NSCLC), sponsored by Takeda. Primary endpoint: Number of Participants with Treatment Emergent Adverse Events (TEAEs) of >=Grade 3 Diarrhea Occurring During the First 4 Cycles of TAK-788 Dosing. Planned start Nov 2020; status: withdrawn.

02

Drugs

mobocertinib
03

Conditions

non-small cell lung cancer (NSCLC)

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