Trial intelligence / Profile preview

PIpepTolDC Vaccine in Type 1 Diabetes

NCT04590872Phase 1Active, not recruiting

Sponsor
City of Hope
Start
Jun 2022
Primary completion
Jun 2024
Modality
Whole Cell Cancer Vaccines, Dendritic Cell Vaccines
Countries
1
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Overview

Phase 1, open-label, single-arm trial of proinsulin peptide-pulsed tolerogenic dendritic cells in type 1 diabetes mellitus (T1D), sponsored by City of Hope. Primary endpoints: Incidence of adverse events up to 2 years, Apheresis duration up to 2 years and 3 more. Started Jun 2022; status: active, not recruiting.

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Drugs

proinsulin peptide-pulsed tolerogenic dendritic cells
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Conditions

type 1 diabetes mellitus (T1D)

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