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Bicarbonate Administration and Cognitive Function in Midlife and Older Adults With CKD
NCT04600323Phase 1Completed
- Sponsor
- University of Colorado Denver
- Start
- Feb 2021
- Primary completion
- Aug 2023
- Modality
- Small Molecules
- Countries
- 1
01
Overview
Phase 1, randomised, double-blind trial in chronic kidney disease (CKD), metabolic acidosis and cognitive dysfunction comparing Placebo with Sodium bicarbonate (2 arms). Primary endpoints: Cognitive Function Composite Score at 12 months, Fluid Cognition Composite Score at 12 months and 1 more. Started Feb 2021; status: completed.
02
Drugs
sodium bicarbonate
03
Conditions
chronic kidney disease (CKD)metabolic acidosiscognitive dysfunction
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