Trial intelligence / Profile preview

Zanubrutinib in Patients With IgG4-Related Disease

NCT04602598Phase 2Completed

Start
Aug 2022
Primary completion
Feb 2025
Modality
Fragment-Derived Small Molecules, Reversible Covalent Inhibitors, Bivalent/Multivalent Binders
Countries
1
01

Overview

Phase 2, open-label, single-arm trial of zanubrutinib in IgG4-related disease (IgG4-RD). Primary endpoints: Volume of the Submandibular Glands on PET-MRI at 24 weeks and Volume of the Lacrimal Glands on PET-MRI at 24 weeks. Started Aug 2022; status: completed.

02

Drugs

zanubrutinib
03

Conditions

IgG4-related disease (IgG4-RD)

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