Trial intelligence / Profile preview

LY3410738 in Advanced Hematologic Malignancies With IDH1 or IDH2 Mutations

NCT04603001Phase 1Active, not recruiting

Sponsor
Eli Lilly and Company
Start
Nov 2020
Primary completion
Jul 2023
Modality
Small Molecules
Countries
12
01

Overview

Phase 1, open-label trial of crelosidenib in acute myeloid leukemia (AML), myelodysplastic syndrome (MDS), chronic myelomonocytic leukemia (CMML) and 1 more (8 arms), sponsored by Eli Lilly and Company. Primary endpoints: Maximum Tolerated Dose / Recommended Phase 2 Dose at 30 months and Overall Response Rate at 30 months. Started Nov 2020; status: active, not recruiting.

02

Drugs

crelosidenib
03

Conditions

acute myeloid leukemia (AML)myelodysplastic syndrome (MDS)chronic myelomonocytic leukemia (CMML)Myeloproliferative Neoplasm (MPN)

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