Trial intelligence / Profile preview

Durvalumab and Tremelimumab Following Radioembolization in Unresectable Locally Advanced Hepatocellular Carcinoma

NCT04605731Phase 1Active, not recruiting

Sponsor
City of Hope
Start
Aug 2021
Primary completion
Feb 2027
Modality
Antibody Conjugates, Engineered Antibody Formats, PD-1/PD-L1 Inhibitors
Countries
1
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Overview

Phase 1, open-label, single-arm trial of durvalumab and tremelimumab in hepatocellular carcinoma (HCC), sponsored by City of Hope. Primary endpoints: Incidence of adverse events, Dose-limiting toxicity at 4 weeks and 1 more. Started Aug 2021; status: active, not recruiting.

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Drugs

durvalumabtremelimumab
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Conditions

hepatocellular carcinoma (HCC)

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