Trial intelligence / Profile preview

JNJ-74856665 (DHODH inhibitor) in AML and MDS

NCT04609826Phase 1Completed

Sponsor
Janssen Pharmaceutical
Start
Nov 2020
Primary completion
Aug 2025
Modality
Small Molecules
Countries
4
01

Overview

Phase 1, open-label trial of JNJ-74856665 in acute myeloid leukemia (AML), myelodysplastic syndrome (MDS) and chronic myelomonocytic leukemia (CMML) (4 arms), sponsored by Janssen Pharmaceutical. Primary endpoints: Dose-Limiting Toxicity at 28 days, Adverse Events at 6 months and 1 more. Started Nov 2020; status: completed.

02

Drugs

JNJ-74856665
03

Conditions

acute myeloid leukemia (AML)myelodysplastic syndrome (MDS)chronic myelomonocytic leukemia (CMML)

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