Trial intelligence / Profile preview

Crizanlizumab in RVCL

NCT04611880Phase 2Completed

Sponsor
Washington University School of Medicine
Start
Jan 2021
Primary completion
Apr 2025
Modality
Monoclonal Antibodies
Countries
1
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Overview

Phase 2, open-label, single-arm trial of crizanlizumab in retinal vasculopathy with cerebral leukoencephalopathy and systemic manifestations (RVCL-S), sponsored by Washington University School of Medicine. Primary endpoint: Change in the Percentage of White Matter Hyperintensity (WMH) Lesion Volume on FLAIR MRI at 1 year. Started Jan 2021; status: completed.

02

Drugs

crizanlizumab
03

Conditions

retinal vasculopathy with cerebral leukoencephalopathy and systemic manifestations (RVCL-S)

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