Trial intelligence / Profile preview

Donafenib and KN046 in Advanced Gastrointestinal Tumors

NCT04612712Phase 2Terminated

Sponsor
Zelgen
Start
Jan 2021
Primary completion
Jun 2022
Modality
Monoclonal Antibodies, Bispecific Antibodies, Small Molecules
Countries
1
01

Overview

Phase 2, open-label, single-arm trial of donafenib and erfonrilimab in gastrointestinal tumor and hepatocellular carcinoma (HCC), sponsored by Zelgen. Primary endpoints: Tolerability of Donafenib in Combination With KN046 at 21 days and Objective Response Rate up to 36 months. Started Jan 2021; status: terminated.

02

Drugs

donafeniberfonrilimab
03

Conditions

gastrointestinal tumorhepatocellular carcinoma (HCC)

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