Trial intelligence / Profile preview

Allogeneic MSC for Corneal Repair

NCT04626583Phase 1Completed

Sponsor
University of Illinois Chicago
Start
Mar 2021
Primary completion
Apr 2023
Modality
Stem Cell Therapies
Countries
1
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Overview

Phase 1, open-label trial of allogeneic bone marrow-derived mesenchymal stromal cells (ICSCYL) in neurotrophic keratitis (NK) and Corneal epithelial defect (3 arms), sponsored by University of Illinois Chicago. Primary endpoints: Treatment Emergent Adverse Events at 28 days and Proportion of participants with improvement in epithelial defect or barrier integrity at 28 days. Started Mar 2021; status: completed.

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Drugs

allogeneic bone marrow-derived mesenchymal stromal cells (ICSCYL)
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Conditions

neurotrophic keratitis (NK)Corneal epithelial defect

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