Trial intelligence / Profile preview

CAR-T for Adult R/R B-ALL Bridging to Allo-HSCT

NCT04626726Phase 1Unknown

Sponsor
Senlang Bio
Start
Apr 2020
Primary completion
May 2023
Modality
Gene Editing, Gene Silencing, CAR-T Cells
Countries
1
01

Overview

Phase 1, open-label, single-arm trial of SENL-B19, anti-CD22 chimeric antigen receptor T cells and SL19+22 CAR-T in B cell acute lymphoblastic leukemia (B-ALL), sponsored by Senlang Bio. Primary endpoints: Number of Participants with Severe/Adverse Events at 28 days and Copies numbers of CAR in peripheral blood(PB) and/or bone marrow(BM) at 24 months. Status: unknown.

02

Drugs

SENL-B19anti-CD22 chimeric antigen receptor T cellsSL19+22 CAR-T
03

Conditions

B cell acute lymphoblastic leukemia (B-ALL)

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