Trial intelligence / Profile preview

APR-548 with Azacitidine in TP53-Mutant MDS

NCT04638309Phase 1Terminated

Sponsor
Aprea Therapeutics
Start
Sep 2021
Primary completion
Apr 2022
Modality
Prodrugs/Conditional Activator Small Molecules
Countries
1
01

Overview

Phase 1, open-label trial of APR-548 in myelodysplastic syndrome (MDS) (3 cohorts), sponsored by Aprea Therapeutics. Primary endpoint: Treatment Emergent Adverse Events at 28 days. Started Sep 2021; status: terminated.

02

Drugs

APR-548
03

Conditions

myelodysplastic syndrome (MDS)

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