Trial intelligence / Profile preview

ADCT-301 in Relapsed or Refractory AML, MDS, or MDS/MPN

NCT04639024Phase 2Terminated

Start
Dec 2021
Primary completion
Nov 2022
Modality
Monoclonal Antibodies, Antibody-Drug Conjugates (ADCs)
Countries
1
01

Overview

Phase 2, open-label, single-arm trial of camidanlumab tesirine in acute myeloid leukemia (AML), myelodysplastic syndrome (MDS) and Myeloproliferative Neoplasm (MPN). Primary endpoints: Complete Remission (CR) or Complete Remission With Incomplete Count Recovery (CRi) at 11 months and Dose Limiting Toxicities at 7 months. Started Dec 2021; status: terminated.

02

Drugs

camidanlumab tesirine
03

Conditions

acute myeloid leukemia (AML)myelodysplastic syndrome (MDS)Myeloproliferative Neoplasm (MPN)

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