Trial intelligence / Profile preview

MAS825 in Monogenic IL-18 Driven Autoinflammatory Diseases

NCT04641442Phase 2Active, not recruiting

Sponsor
Novartis
Start
Dec 2020
Primary completion
Oct 2025
Modality
Bispecific Antibodies, Monoclonal Antibodies
Countries
7
01

Overview

Phase 2, randomised, double-blind trial in NLRC4-associated autoinflammatory syndrome, X-linked inhibitor of apoptosis protein deficiency and necrotizing enterocolitis (NEC) comparing MAS825 with Placebo (2 arms). Primary endpoint: Occurrence of disease flare up to 6 months. Started Dec 2020; status: active, not recruiting.

02

Drugs

MAS825
03

Conditions

NLRC4-associated autoinflammatory syndromeX-linked inhibitor of apoptosis protein deficiencynecrotizing enterocolitis (NEC)

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