Trial intelligence / Profile preview

STP705 for Advanced Liver Tumors

NCT04676633Phase 1Completed

Sponsor
Sirnaomics
Start
Mar 2021
Primary completion
Jan 2023
Modality
Nanoparticles, Conjugated siRNA, Chemically Modified siRNA
Countries
1
01

Overview

Phase 1, open-label trial of sirna-tgf-b1 + sirna-cox-2 in cholangiocarcinoma (CCA), hepatocellular carcinoma (HCC) and liver metastases (5 cohorts), sponsored by Sirnaomics. Primary endpoints: Maximum Tolerated Dose at 28 days and Limited Dose Toxicity at 28 days. Started Mar 2021; status: completed.

02

Drugs

sirna-tgf-b1 + sirna-cox-2
03

Conditions

cholangiocarcinoma (CCA)hepatocellular carcinoma (HCC)liver metastases

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