Trial intelligence / Profile preview

CXCR4 Modified CD19 CAR-T in Relapsed/Refractory B-cell Malignancies

NCT04684472Phase 1Unknown

Start
Mar 2021
Primary completion
Jan 2023
Modality
CAR-T Cells
Countries
1
01

Overview

Phase 1, open-label, single-arm trial of cxcr4-modified anti-cd19 car t cells in B cell acute lymphoblastic leukemia (B-ALL) and B-cell non-Hodgkin lymphoma. Primary endpoints: Incidence of treatment-emergent adverse events up to 5 years and Dose-limiting toxicity at 28 days. Status: unknown.

02

Drugs

cxcr4-modified anti-cd19 car t cells
03

Conditions

B cell acute lymphoblastic leukemia (B-ALL)B-cell non-Hodgkin lymphoma

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