Trial intelligence / Profile preview

DESTINY-Lung03: T-DXd and Immunotherapy With/Without Chemotherapy in First-line HER2-overexpressing NSCLC

NCT04686305Phase 1Recruiting

Sponsor
AstraZeneca
Start
Mar 2021
Primary completion
Jun 2027
Modality
Monoclonal Antibodies, Antibody-Drug Conjugates (ADCs), Small Molecules
Countries
19
01

Overview

Phase 1, randomised, open-label trial of trastuzumab deruxtecan in non-small cell lung cancer (NSCLC) (10 arms), sponsored by AstraZeneca. Primary endpoint: Frequency of Adverse Events and Serious Adverse Events at 20 months. Started Mar 2021; status: recruiting.

02

Drugs

trastuzumab deruxtecan
03

Conditions

non-small cell lung cancer (NSCLC)

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