Trial intelligence / Profile preview

JDQ443 in Advanced Solid Tumors with KRAS G12C Mutation

NCT04699188Phase 2Active, not recruiting

Sponsor
Novartis
Start
Feb 2021
Primary completion
Jan 2027
Modality
Small Molecules
Countries
16
01

Overview

Phase 2, randomised, open-label trial of opnurasib in solid tumor, non-small cell lung cancer (NSCLC) and colorectal cancer (CRC) (4 arms), sponsored by Novartis. Primary endpoints: Dose Limiting Toxicities at 21 days, Adverse Events and Serious Adverse Events at 24 months and 4 more. Started Feb 2021; status: active, not recruiting.

02

Drugs

opnurasib
03

Conditions

solid tumornon-small cell lung cancer (NSCLC)colorectal cancer (CRC)

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