Trial intelligence / Profile preview

CCL Vario System for Corneal Collagen Cross-Linking

NCT04731727Phase 1Not yet recruiting

Start
Jun 2021
Primary completion
Dec 2026
Modality
Orthosteric Ligands, Metabolically Activated Prodrugs
01

Overview

Phase 1, open-label, single-arm trial of riboflavin in keratoconus, corneal ectasia, Pellucid marginal degeneration (PMD) and 1 more. Primary endpoints: Best Corrected Visual Acuity at 1 year, Uncorrected Visual Acuity at 1 year and 1 more. Planned start Jun 2021; status: not yet recruiting.

02

Drugs

riboflavin
03

Conditions

keratoconuscorneal ectasiaPellucid marginal degeneration (PMD)keratitis

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