Trial intelligence / Profile preview

Sozinibercept (OPT-302) + Aflibercept in wet AMD (COAST)

NCT04757636Phase 3Terminated

Sponsor
Opthea Limited
Start
Mar 2021
Primary completion
Mar 2025
Modality
Antibody Fragments, Fc-Fusion Proteins
Countries
30
01

Overview

Phase 3, randomised, double-blind trial of sozinibercept in neovascular age-related macular degeneration (NVAMD) (3 arms), sponsored by Opthea Limited. Primary endpoint: Mean Change in Early Treatment Retinopathy Study (ETDRS) Best-corrected Visual Acuity (BCVA) Letters at 52 weeks. Started Mar 2021; status: terminated.

02

Drugs

sozinibercept
03

Conditions

neovascular age-related macular degeneration (NVAMD)

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